For Quick Relief From Arthritis, Backaches, Muscle Aches, Sprains, Cramps. For Quick Relief From Arthritis, Backaches, Muscle Aches, Sprains, Cramps. Directions: Apply generously and massage gently into the affected area. Repeat as necessary up to 4 times daily.
As a topical agent, it acts as a counter-irritant by imparting a cooling effect and by initially stimulating nociceptors and then desensitizing them. Topically applied menthol may also activate central analgesic pathways. At high concentrations, menthol may generate cold allodynia.
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